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The undefeated Atlanta Falcons are slight road favorites on the NFL betting lines for this week as they try to pick up their first ATS win over the New Orleans Saints since 2010. That early Sunday afternoon matchup highlights Week 10 of the NFL schedule.

Rarely does a matchup of two teams with a combined record of 5-9 deserve as much attention as Monday night's matchup between the 2-5 New Orleans Saints and 3-4 Philadelphia Eagles at the Superdome (8:30 pm ET, ESPN).

On one side we have a team in the Saints still suffering from the after-affects of a murky scandal involving hits for money, playing without its suspended head coach and unable to stop anybody on defense.

On the other side we have a supposed “Dream Team” in the Eagles that's played its head coach onto a hot seat.

The Arizona Cardinals have lost four games in a row as they head into their matchup on Sunday afternoon on the road against the Green Bay Packers as the biggest underdog on the NFL betting board. As well, with the Cardinals at 1-7 on the OVER/UNDER the contest will attract the attention of totals bettors at the sportsbooks.

The San Francisco 49ers have not played very well over their last couple of games, but they still lead the NFC West. San Fran gets a chance to build on that lead when it visits Phoenix to take on the Arizona Cardinals on this week's edition of Monday Night Football (8:30 pm ET, ESPN).

The Niners got off to a 4-1 start this season, with victories over the Packers, Lions and Jets along the way. But San Francisco then looked terrible in losing an NFC championship game rematch at home to the Giants 26-3, getting outrushed 149-80 and turning the ball over three times.

The New York Jets are under .500 on the season, but they've been the best wager amongst the AFC East teams so far in 2012. The Jets will play host to the division-rival Miami Dolphins on Sunday afternoon as we look at the betting action on the schedule for Week 8 of the NFL season.

The Jets are just 3-4 so far in 2012, and they're coming off a 29-26 loss to the New England Patriots last week. However, New York is also a lucrative 5-2 ATS on the season, and one of those covers came back in Week 2 when they beat the Dolphins by a score of 23-20 in Miami as a 2.5-point favorite.