Charlotte 49ers Game Logs
| event date | Opponent | Type | Result | score | ATS | Line | OU | Total | preview available | recap available |
|---|---|---|---|---|---|---|---|---|---|---|
| Sep 3, 2021 | vs Duke | REG | W | 31-28 | W | 6.5 | U | 60 | Preview | Recap |
| Sep 11, 2021 | vs Gardner-Webb | REG | W | 38-10 | W | -23 | U | 58 | Preview | No |
| Sep 18, 2021 | @ Georgia State | REG | L | 20-7 | L | 4.5 | U | 63 | Preview | Recap |
| Sep 24, 2021 | vs Middle Tennessee | REG | W | 42-39 | P | -3 | O | 55.5 | Preview | Recap |
| Oct 2, 2021 | @ Illinois | REG | L | 24-14 | P | 10 | U | 54 | Preview | Recap |
| Oct 8, 2021 | @ Florida International | REG | W | 45-33 | W | -3.5 | O | 60.5 | Preview | Recap |
| Oct 21, 2021 | vs Florida Atlantic | REG | L | 38-9 | L | 6.5 | U | 58 | Preview | Recap |
| Oct 30, 2021 | @ Western Kentucky | REG | L | 45-13 | L | 19.5 | U | 72 | Preview | Recap |
| Nov 6, 2021 | vs Rice | REG | W | 31-24 | W | -6.5 | O | 52.5 | Preview | Recap |
| Nov 13, 2021 | @ Louisiana Tech | REG | L | 42-32 | L | 7 | O | 58 | Preview | Recap |
| Nov 20, 2021 | vs Marshall | REG | L | 49-28 | L | 14.5 | O | 62 | Preview | Recap |
| Nov 27, 2021 | @ Old Dominion | REG | L | 56-34 | L | 8.5 | O | 56 | No | Recap |