Southern Miss Golden Eagles Game Logs
| event date | Opponent | Type | Result | score | ATS | Line | OU | Total | preview available | recap available |
|---|---|---|---|---|---|---|---|---|---|---|
| Sep 4, 2021 | @ South Alabama | REG | L | 31-7 | L | 2 | U | 56.5 | Preview | Recap |
| Sep 11, 2021 | vs Grambling State | REG | W | 37-0 | W | -23 | U | 47.5 | Preview | No |
| Sep 18, 2021 | vs Troy | REG | L | 21-9 | L | 11 | U | 49.5 | Preview | Recap |
| Sep 25, 2021 | @ Alabama | REG | L | 63-14 | L | 45 | O | 58 | Preview | Recap |
| Oct 2, 2021 | @ Rice | REG | L | 24-19 | L | 1 | U | 45 | Preview | Recap |
| Oct 9, 2021 | vs Texas El Paso | REG | L | 26-13 | L | 1.5 | U | 46.5 | Preview | Recap |
| Oct 16, 2021 | vs Alabama-Birmingham | REG | L | 34-0 | L | 17 | U | 43.5 | Preview | Recap |
| Oct 30, 2021 | @ Middle Tennessee | REG | L | 35-10 | L | 12.5 | U | 47 | Preview | Recap |
| Nov 6, 2021 | vs North Texas | REG | L | 38-14 | L | 5.5 | O | 49 | Preview | Recap |
| Nov 13, 2021 | @ Texas-San Antonio | REG | L | 27-17 | W | 32.5 | U | 54.5 | Preview | Recap |
| Nov 19, 2021 | @ Louisiana Tech | REG | W | 35-19 | W | 15.5 | O | 47.5 | Preview | Recap |
| Nov 27, 2021 | vs Florida International | REG | W | 37-17 | W | -14.5 | O | 46 | No | Recap |